Liver disease
A global health concern
With increasing prevalence, Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) is the most common cause of chronic liver disease worldwide and a growing public health concern. It is a silent condition that can progress from steatohepatitis into fibrosis, and eventually cirrhosis – a major factor for liver transplants and mortality.
Canon’s liver analysis package offers proven methods for multiparametric screening, assessment and staging of liver disease. Within minutes, you can obtain a comprehensive liver status during a routine examination, establish a diagnosis for your patient and potentially reduce time-consuming and invasive biopsies.
Staging Steatotic Liver Disease (SLD)
Take a holistic view of your patients
A host of non-invasive tools are available for clinicians to assist in the assessment and quantification of the full spectrum of liver disease, providing easy-to-understand clinical reports and guidance in both visual and quantitative formats.
Early detection
Aplio can provide superior image quality and contrast resolution. This may allow clinicians to improve the early detection of morphological changes and pathologies.
Aplio can provide superior image quality and contrast resolution. This may allow clinicians to improve the early detection of morphological changes and pathologies.
Non-invasive staging
Aplio’s powerful screening and analysis tools are designed for ultrasound-based imaging, assessment and disease staging in the daily routine.
Aplio’s powerful screening and analysis tools are designed for ultrasound-based imaging, assessment and disease staging in the daily routine.
Comprehensive quantification tools
Referenced in independent clinical studies, Aplio’s wide range of quantification tools are safe and efficient for staging and treatment follow-up.
Referenced in independent clinical studies, Aplio’s wide range of quantification tools are safe and efficient for staging and treatment follow-up.
Sophisticated intervention
Aplio’s specialised transducers, imaging and navigation tools can help you perform interventional procedures and their follow-up efficiently and with confidence.
Aplio’s specialised transducers, imaging and navigation tools can help you perform interventional procedures and their follow-up efficiently and with confidence.
Precise follow-up
In combination with the system’s onboard reporting, Aplio offers a wide range of dedicated tools and the ability to directly compare with previous exams for reliable follow-up.
In combination with the system’s onboard reporting, Aplio offers a wide range of dedicated tools and the ability to directly compare with previous exams for reliable follow-up.
Multi Parametric Reporting
Aplio can combine the results of ultrasound and other clinical results into a single report for a more complete understanding of a patient's examination status.
Aplio can combine the results of ultrasound and other clinical results into a single report for a more complete understanding of a patient's examination status.
Liver analysis package
Efficient screening and diagnostics
The earliest possible detection and characterisation of diffuse liver disease is important for determining a prognosis and, particularly in case of early, reversible stages, for an effective, closely monitored therapy. Canon offers a seamless package that is directly applicable in your clinical routine.
Reversible tissue changes
Attenuation Imaging (ATI) is an innovative tool that may assist clinicians in assessing the degree of steatosis. The early characterisation of an existent steatosis is important for a reliable prognosis as well as for an effective therapy. ATI provides a color-coded visualisation of the frequency-dependent attenuation coefficient in liver tissue.
Inflammatory processes
Innovative Shear Wave Dispersion (SWD) imaging, which is currently under clinical evaluation, allows mapping of shear wave propagation for the isolated assessment of parenchymal viscosity. The color-coded display may provide valuable, additional information that can aid in subsequent patient management.
Hepatic fibrosis
Depending on the degree of fibrosis, the hepatic parenchyma exhibits increased viscoelasticity. Clinicians examine liver stiffness as one of the indicators for diagnosing liver fibrosis or cirrhosis. Liver stiffness can be measured using Shear Wave Elastography (SWE).
Suspicious lesions
Advanced modes including Contrast Enhanced Ultrasound (CEUS) quantification can provide detailed insights into perfusion dynamics. Clinicians desire accurate imaging of contrast uptake to identify lesions. The CEUS package provides visualisation of ultrasound signals from contrast agents.
Comprehensive quantification tools
Elaborate workflow for confident decision-making
With just a few clicks, Canon’s comprehensive Liver Package allows you to capture a comprehensive status in minutes, providing robust measurement results that can support a reliable diagnosis. Summarised in a concise report, the readings may allow clinicians to make fast assessments and treatment decisions and support regular patient follow-up.
Faster, reliable results
As much as we at Canon strive to provide high quality imaging and quantitative measurement techniques, it is important to us that the results are available quickly and easily. That’s why we work with our users to develop innovative operating concepts and workflow automation solutions, that can allow you to achieve comprehensive, consistent results in less time.
Smart Maps help you visualise shear wave propagation in real time. Canon’s unique propagation map is a powerful and intuitive tool to visually assess the quality of an elastogram.
Canon's unique Quad view mode enables simultaneous comparative display of shear wave velocity, elasticity, propagation and dispersion for a more comprehensive, reliable assessment of the liver status.
ATI and SWE can be evaluated simultaneously with a single scan. With this, clinicians may assess hepatic steatosis and fibrosis even faster and more efficiently.
Multi Parametric Report
The Multi Parametric Report summarises all results of your liver examination including external measurements such as liver size or blood tests such as the AST/ALT ratio. A colored bar graph or spider graph informs you, your patients and their referrers quickly and clearly about the status of the liver.
ATI trend graph
The ATI trend chart allows the user to intuitively view and analyse measurement results, over the course of therapy. Selecting a previous data point in the ATI trend chart automatically triggers the display of a graph showing all other corresponding measurements obtained for that day.
User experience
Prof. Hayato Nakagawa, MD, PhD
Mie University Graduate School of Medicine
Mie, Japan
“The use of diagnostic ultrasound systems in gastroenterological medicine”
Mie University Graduate School of Medicine
Mie, Japan
“The use of diagnostic ultrasound systems in gastroenterological medicine”
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Education & resources
Clinical Case Studies
» “The Aplio's shear wave application supplies the user with multiple indicators of the reliability of the shear wave propagation. These tools should be used in all cases. The operator should consider using a combination of continuous and one-shot modes, especially when working with a non-compliant patient” «
»“The most outstanding feature was the newly developed abdominal curve transducer 8C1. This transducer has the penetration and contrast resolution to scan through my bariatric patients with liver depths of 23 cm.” «
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