Liver Analysis Package

Diffuse non-viral liver disease is an increasing burden on the Australian health system. Up to 40 % of people over 60 have fatty liver disease and an increasing trend of the condition is being seen in school aged children. Fatty liver disease is related to life-style factors, such as excessive alcohol consumption and can lead to cirrhosis and liver failure.

The AplioTM series diagnostic ultrasound system incorporates the latest generation architecture and advanced transducer technology to deliver a new level of image quality. The newly developed liver tools aim to support clinicians to evaluate diffuse liver disease easier and faster.

Liver disease imaging is one of the major challenges faced by clinicians due to a wide range of pathologies that have overlapping appearances on medical imaging. To provide the diagnostic confidence and clarification needed, new and unique imaging tools have been developed to allow visualisation of changes in liver status. 

Ultrasound diagnosis of the fatty liver using B mode is difficult to reproduce and has a high degree of inter observer error. The ability to accurately and non-invasively grade the degree of “fatty” will help clinicians diagnose this condition more accurately and earlier.

Contact us

i-series Liver Analysis

Covering the full range of Liver disease

Liver disease is one of the major challenges in imaging today, with a wide range of pathologies. To provide the diagnostic confidence needed, new and unique imaging tools have been developed to allow visualisation of changes in liver status.

*Available on Aplio i800 only

Attenuation Imaging (ATI)*

Provides the capability to quantify and colour-code the changes in the attenuation coefficient of the liver. More attenuation may arise with changes in liver composition (e.g., increased fat levels).

Using statistical analysis of the attenuation throughout the region of interest, the system is able to quantify the accuracy of the sample. This provides information regarding the uniformity of the attenuation which is important for accuracy.

  • As the ultrasound wave is transmitted though tissue, it is attenuated through the process if scatter, absorption and heat.
  • The amount of attenuation is proportional to the frequency.

*Available on Aplio i800 only

Shear Wave Dispersion (SWD)*

Adds the evaluation of tissue viscosity to the routine stiffness assessment of Shear Wave Elastography.

Tissue stiffness changes are common in liver disease, but any viscosity changes associated with disease processes such as fatty infiltration were not able to be assessed until now. The combination of SWE and SWD adds both stiffness and viscosity information for a more complete liver assessment.

In cases of liver inflammation, the liver becomes more viscous (or sticky).  It is these changes that SWD is quantifying.

*Available on Aplio i800 only

Shear Wave Elastography*

Non-invasive, quantitative assessment of tissue stiffness for confident diagnosis.

Canon Medical Systems' Shear Wave technology provides a quantitative measure and dynamic visual display of tissue stiffness in a variety of clinical settings.

  • Overcoming complications / limitations of biopsy 
  • 5 smart maps to visualise and quantify shear wave propagation in real time, including new variance map 
  • Canon unique propagation maps actually show shearwave propagation through the tissue 
  • This assists in measurement placement ensuring accuracy, reproducibility and best practice
  • One shot or continuous mode scanning allowing multiple measurements from one acquisition and quicker examination times
  • Push pulse optimised for deeper regions

*Available on Aplio i-series, Aplio a-series, Aplio 300 and 500 Platinum, Xario 200 Platinum systems


Shear waves are generated by means of an ultrasonic burst (left). Depending on tissue properties, shear waves travel at varying speed. Canon Medical Systems' unique propagation mode can be used to confirm the quality of the shear wave generation (right).


Multi-Parametric Report*

Reporting for Liver Applications

Multi parametric report which can combine results from both ultrasound as well as external exams (such as blood tests) for a combined result. This unique ability to bring multiple test results and combine into a single report can allow a more comprehensive understanding of liver status.

Results can be viewed in tabular format or as a spider plot (where the shape of the combined result mapping can give information on relationships between results in a visual way).

Multi parametric report for the following the liver applications:

  • Shear Wave Elastography 
  • Shear Wave dispersion map 
  • Attenuation imaging 
  • User registration label measurement

*Available on Aplio i800 only

Transducer Technology

Ultra-wideband Multi-Frequency iDMS Convex (i8CX1)*

Covers the same bandwidth as two conventional transducers.

Aplio's Ultra-wideband i-series, provides superior sensitivity and resolution for both near and far field. The ability to use one transducer across a wider range of patient types can potentially reduce cost, while providing better imaging.


Features:

  • Up to 50 cm penetration

Multi-Frequency Slim Face Convex (i8C1)*

Enables easy intercostal scanning and more.


This narrow face transducer features:

  • Improved shape for easy grip 
  • Super lightweight transducer head 
  • Light weight, thin & highly flexible cable

Multi-Frequency Micro-Convex (8MC1)*

The advantages of a curved array in a small footprint.

Aplio's i-series Thin Micro-Convex provides maneuverability and ease-of-access.


New Features:

  • Single crystal technology 
  • Lightweight and maneuverable 
  • New CIVCO® Verza™ Guidance System

Clinical Applications:

  • Abdominal 
  • Pediatric 
  • OB 
  • Biopsy Guidance

White Papers

Approaches to liver tumours

Staging of diffuse liver disease is fundamental for risk quantification before a patient suffers from unrecoverable end-stage liver disease such as cirrhosis and HCC. On the AplioTM i-series, three innovative applications are imbedded for diagnosing diffuse liver disease by assessing liver characteristics: Shear Wave Elastography (SWE) for liver stiffness, Shear Wave Dispersion (SWD) for liver viscosity, and Attenuation Imaging (ATI) for attenuation in liver.

Download

Laparoscopic liver resection as a less invasive treatment option for hepatocellular carcinoma

In this white paper, Dr. Satoru Seo, Department of Surgery from the Graduate School of Medicine, Kyoto University, shared his clinical impressions of the PET-805LA transducer used in combination with the AplioTM Platinum Series diagnostic ultrasound system and discussed the clinical usefulness of intraoperative contrast-enhanced ultrasound.

Download

» “The Aplio's shear wave application supplies the user with multiple indicators of the reliability of the shear wave propagation. These tools should be used in all cases. The operator should consider using a combination of continuous and one-shot modes, especially when working with a non-compliant patient” «

»“The most outstanding feature was the newly developed abdominal curve transducer 8C1. This transducer has the penetration and contrast resolution to scan through my bariatric patients with liver depths of 23 cm.” «

Contact Us