Alphenix solutions for
interventional neuroradiology

Innovative technologies optimised for neurovascular intervention, including the world’s first high definition flat panel detector help you deliver the best possible outcomes for your patients.

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See and deploy complex devices with confidence

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New Alphenix Hi-Def Detector

Visualisation like never before with Canon Medical's first High-Definition (Hi-Def) mode*

The Alphenix interventional systems feature the world’s first high definition (Hi-Def) detector with 76 micron pixel imaging mode. With more than twice the spatial resolution of conventional flat panel detectors (FPD), the Hi-Def detector helps clinicians visualise fine details and anatomical structures, and deploy devices with accuracy and confidence.

The unique Hi-Def imaging mode allows you to effortlessly zoom up to 4cm (1.5”) without losing image quality.

*Available as an option only

Learn more about High-Definition Flat Panel Detector (HD FPD)

New High-Definition Detector

"All those things which the device does that were impossible to see with conventional flat panel detectors become overly abundant1."

- Adnan Siddiqui MD, PhD, FAHA

Vice-Chairman and Professor of Neurosurgery
SUNY University at Buffalo
Director, Neurosurgical Stroke Services, Kalieda Health
Chief Medical Officer, Jacobs Institute

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Complete head-end access flexibility

Alphenix floor- and ceiling-mounted C-arms support complex neurology procedures with an unprecedented range of head-end patient access.

The Alphenix C-arm is designed to move around you and your patient, so procedures can be performed comfortably, safely and efficiently.

Flexible Lateral Isocentre (FLIC) allows the lateral arm of a biplane system to be height adjusted independently, enabling patient anatomy to be kept at isocentre. In a study by Borota and Patz (2017), the use of FLIC led to a 25% reduction in dose, whilst improving ergonomics and range of table heights and increasing angulation ability on the frontal arm1.

1Borota L, Jangland L, Aslund PE, et al. Spot fluoroscopy: a novel innovative approach to reduce radiation dose in neurointerventional procedures. Acta Radiol. 2017;58(5):600-608.


Enhanced workflow to give you greater control and flexibility

The new tableside Alphenix Tablet gives you control right at your fingertips to deliver a faster and more seamless workflow.


Navigate faster with confidence and accuracy

Improved DSA and 2D roadmap with real-time auto pixel shift to automatically correct the position of the mask image due to body motion. Alpha CT can be used to obtain CT-like 3D imaging data from the C-arm. Superimpose this 3D data or prior CT/MR data with the live fluoro display to guide device placement with greater confidence. Comprehensive planning tools, such as cerebral aneurysm analysis allow for quick and intuitive stent sizing and positioning prior to treatment


Dose Tracking System

DTS is a patient-centric model that records the patient’s skin dose in real-time according to c-arm angle, field of view, tube current and imaging mode to give the most accurate demonstration of dose received during an examination. 

Real-time dose monitoring and visualisation allows the operator to modify their approach during procedures to avoid regions where dose thresholds could be exceeded.
A study by The St George Hospital found that use of advanced Dose Reduction Technology (DTS) resulted in a 46% reduction in peak skin dose. Researchers confirmed that ongoing real-time dose feedback is a critical factor in the successful modification of operator behaviour to reduce radiation dose. *

*Wilson S, Prasan AM, Virdi A, et al. Real-time colour pictorial radiation monitoring during coronary angiography: effect on patient peak skin and total dose during coronary angiography. EuroIntervention 2016;12: 939–47.


Spot ROI – Up to 85% Reduction in dose

The unique Spot ROI collimator filter allows the operator to reduce dose to surrounding anatomy while simultaneously ensuring full image quality in the area that matters most.

Spot ROI: 
  • Can be positioned anywhere with the Field of View (FOV) 
  • Can be used to significantly reduce dose during fluoroscopic and DA runs 
  • Allows the operator to monitor the position of your guide wire and the surrounding anatomy, at significantly lower dose


Spot Fluoro - Reduce scatter radiation by up to 50% with advanced collimation

See a more complete picture with less dose to surrounding anatomy. Spot Fluoro enables the operator to collimate a rectangular or square region of interest (ROI) anywhere within the general field of view.
  • Reduce cumulative dose area product by up to 50%**  
  • Reduce scatter radiation by more than 50%**, enabling safer procedures for patients and interventional staff  
  • Freely collimate anywhere on the image with asymmetric blade movements   
  • Last Image Hold (LIH) overlay with live fluoroscopy    
  • Next generation automatic brightness control with scatter correction, providing optimal image quality and clarity where you need it
**Borota L, Jangland L, Aslund PE, et al. Spot fluoroscopy: a novel innovative approach to reduce radiation dose in neurointerventional procedures. Acta Radiol. 2017;58(5):600-608

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Live Zoom

Image Magnification without Dose Penalty

  • 50% dose reduction compared to geometric magnification
  • Digitally magnify the image display without increasing detector input dose  
  • Increases image display size in real-time during both fluoroscopy and digital acquisition (DA,) offering dose savings compared to traditional FOV magnifications   

                                            13cm FOV - Fluoro

                                    13cm FOV + Live Zoom 1.4 - Fluoro

Interventional Neuroradiology


The Alphenix systems provide a comprehensive suite of advanced imaging tools to enhance visualisation. Applications are integrated into the new feature-rich workstation to improve workflow.

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3D Angio

Fast and Intuitive Workflow

The fastest single plane, ceiling mounted C-arm available. The Alphenix allows rotations up to 80 deg/sec to provide faster 3D and cone beam CT times.

3D Roadmap

Turn 3D Acquisitions into Live Fluoro Roadmaps

3D image display changes according to the system conditions such as the C-arm angle, SID, field size, tabletop height, and tabletop panning.

3D Roadmap

Alpha CT

Enhanced visualisation

To supplement 3D imaging, CT-like Imaging is available to support visualisation of anatomy or pathology during interventional procedures.

• Head         • Neck
• Body         • Device
• Vessel       • MAR

Alpha CT

Cerebral Artery Analysis (CAA)

Enhanced visualisation

This application is intended to facilitate the extraction and segmentation of user identified aneurysms on the cerebral arteries from cerebral angiography data, allowing morphological characteristics to be assessed.

Cerebral Artery Analysis (CAA)

Instant Roadmap

Improved workflow and productivity

Instant and automatic creation of a mask image after DSA acquisition, which is reflected to fluoroscopy roadmap without any manipulation or input from user.

Instant Roadmap

Multi-Modality Fusion

Enhanced visualisation during interventional procedures.

Canon Medical's roadmap function enables 3D CT or MR Volume data to be superimposed on the live fluoro display. This feature provides additional views of the vascular anatomy to aid clinicians during interventional procedures.

Needle Guidance

CT or XA Datasets

Needle guidance function enables positioning of the C-arm to the optimum viewing position and display of a puncture guide line for assistance.

Needle Guidance

Parametric Imaging1

  • Video playback with Colour Coded Circulation
  • Displays an entire image sequence as a single composite image
  • Colour coded in order to characterise contrast media dynamics and allow easier visual evaluation of patients

Parametric parameters include:
  • Time To Peak (TTP) 
  • Time To Peak Alpha (TTPα) 
  • Peak Height (PH) 
  • Area Under Curve (AUC) 
  • Time To Arrival (TTA) 
  • Time To Arrival Alpha (TTAα) 
  • Mean Transit Time (MTT) 

¹Parametric Imaging software is not intended for stand-alone use or diagnosis.


The smart investment choice

Whatever your clinical needs, versatile space-saving configurations make refitting existing suites an economical option. Alphenix systems seamlessly integrate into your HIS and PACS networks. Improvements in functionality, speed and workflow efficiency boost system utilisation and productivity. In addition, lower energy consumption, flexible upgrade options and Canon Medical’s industry-recognised customer service, all help you get the best out the system once installed.
Alphenix Biplane Hi-Def: A Point Where Cutting-Edge Technologies and Fine Art Meet

The High Definition function offers not only excellent visualisation of the smallest anatomical structures and the smallest devices and their ultrastructure, but also offers the operator a unique visual, artistic experience. 

- Dr. Ljubisa Borota, Uppsala University, Sweden
Canon Medical Publications
Neuroendovascular Treatment Using an Angiography System with the Hi-Def Detector

CAA includes a semiautomatic function that allows the user to perform setting and editing during neckline determination in cerebral aneurysm volume analysis. This is a very useful tool for formulating the optimal treatment strategy.

- Dr. Tetsu Satow, Chief Physician, Department of Neurosurgery
Canon Medical Publications
Benefits Using High-Definition (Hi-Def) Technology in Complex Neurovascular Procedures

The Hi-Def technology by Canon Medical, provides a new visualisation gateway to clinically expand the horizons of neuro intervention beyond the standard conventional imaging technology today. 

- Adnan Siddiqui MD, PhD, FAHA
Canon Medical Publications
Experience using the New Alphenix Interventional System for Neuro-endovascular Therapy

During neurovascular therapy being able to see the intricate details in anatomy, and access devices gives us the confidence to quickly and better treat our patients with less chance of complications.  

- Prof. Ichiro Nakahara, Department of Comprehensive Strokology, Fujita Health University Hospital
Canon Medical Publications
Initial investigations of a special high-definition (Hi-Def) zoom capability in a new detector system for neuro-interventional procedures

The Hi-Def zoomed images were much preferred over the FPD, indicating the potential to improve endovascular procedures and hence outcomes using such a Hi-Def feature.

S.V. Setlur Nagesh et al, NCBI
Quantitative comparison of Hi-Def and FPD zoom modes in an innovative detector using Relative Object Detectability (ROD) metrics

Due to their higher resolution, high-definition-mode images are sharper and visually preferred compared with the flat panel detector images. The improved imaging provided by the high-definition mode can potentially provide an advantage during neurointerventional procedures.

J. Krebs et al, SPIE Digital Library
SPIE Digital Library
High-Definition Zoom Mode, a High-Resolution X-Ray Microscope for Neurointerventional Treatment Procedures: A Blinded-Rater Clinical-Utility Study

Each of the metrics demonstrated improved performance of the Hi-Def zoom mode over the standard FPD mode in imaging a wide array of objects such as stents, wires, and spheres. Of particular note is the greater performance of the Hi-Def when considering the high spatial frequencies necessary for visualising fine image details of a pipeline stent.

S.V. Setlur Nagesh et al, American Journal of Neuroradiology
American Journal of Neuroradiology
Refine and Redefine Intervention Using High-Definition (Hi-Def) Technology

Andrew Kuhls-Gilcrist, PhD, DABR, Mark Hohn, Dale Marek, RT(R), Yiemeng Hoi, PhD Medical Affairs, Interventional X-ray, Canon Medical Systems USA, Inc.

Swetadri Vasan Setlur Nagesh, PhD, Stephen Rudin, PhD, FAAPM, Adnan Siddiqui, MD, PhD, FACS, FAHA, FAANS Canon Stroke and Vascular Research Centre University at Buffalo, Buffalo, NY
Read white paper
High Definition Imaging Reduces Procedure Time Without Impacting Patient Dose in Image-Guided Neuro Interventional Procedures.

Swetadri Vasan Setlur Nagesh, MS,PhD, Buffalo, NY (Presenter) Nothing to Disclose
Read article (link to external website)
Single-centre experience of using high definition (Hi-Def) imaging during neurointervention treatment of intracranial aneurysms using flow diverters.

PSwetadri Vasan Setlur Nagesh1,2, Kunal Vakharia2,3, Muhammad Waqas2,3, Stephan A Munich2,3, Daniel R Bednarek1,2,4, Jason M Davies2,3,5, Kenneth V Snyder2,3, Maxim Mokin6, Stephen Rudin1,2,4,7,8,9, Elad I Levy1,2,3,4, Adnan H Siddiqui 1,2,3,4
Read article (link to external website)
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